1例Ⅳ期肝癌术后患者并发免疫检查点抑制剂相关重症肌无力危象前状态的护理 [中文引用][英文引用]

总结 1 例Ⅳ期肝癌术后患者并发免疫检查点抑制剂（immune checkpoint inhibitors，ICIs）相关重症肌无力危象前状态的护理经验。护理要点：密切监测病情，早期识别肌无力危象前状态；成立多学科团队全病程管理，改善患者呼吸功能、口咽肌功能与眼部功能，控制呼吸道感染，加强心理护理，预防患者发展为肌无力危象（myasthenia gravis crisis，MC）；联合用药缓解患者肌无力症状，预防药物不良反应；个性化康复运动训练促进肌力恢复。患者住院期间未进展为 MC，治疗 20d 顺利出院，3个月随访患者康复良好。

The nursing experience was summarised over a patient who developed an impending myasthenic crisis following immune checkpoint inhibitors（ICIs）therapy after the surgery for stage-IV liver cancer. Key nursing points included：close monitoring for early signs of impending myasthenic crisis；set up a multi-disciplinary team to improve respiratory，oropharyngeal and ocular function， control respiratory infection，provide psychological support in order to prevent the patient from developing a manifest myasthenia-gravis crisis（MC）；combine with medications to relieve myasthenic symptoms and prevent adverse drug reactions；individualised rehabilitation training to promote recovery of muscular strength. Eventually，the patient did not develop into a MC during hospitalisation（20d）and was well at 3-month after discharge